Protracted Renal Clearance of Fentanyl in Persons with Opioid Use Disorder
Fentanyl is highly lipophilic and can be stored in adipocytes (Roy and Flynn, 1988; Pöyhiä and Seppälä, 1994), which likely accounts for the protracted clearance observed in this study. It is also unclear whether norfetnanyl acts on the mu-opioid receptor and what effect that might have on analgesic and euphorigenic outcomes. Participants had a mean…
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